Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.53 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 7/20 | 0.46 |
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10154066 | 0.84 | KIF11 (0.60) | KIF11DGAT1RAB9ANPC1TP53 | |
| SCHEMBL10154080 | 0.84 | KIF11 (0.60) | KIF11DGAT1RAB9ANPC1TP53 | |
| SCHEMBL30337602 | 0.84 | CYP11B1 (0.55) | RAB9ANPC1TP53ALDH1A1KMT2A | |
| SCHEMBL25094279 | 0.79 | KIF11 (0.55) | KIF11DGAT1RAB9ANPC1TP53 | |
| SCHEMBL10154177 | 0.79 | KIF11 (0.55) | KIF11DGAT1RAB9ANPC1TP53 | |
| SCHEMBL25515089 | 0.78 | KIF11 (0.50) | KIF11DGAT1RAB9ANPC1TP53 | |
| SCHEMBL10154180 | 0.76 | KIF11 (0.51) | KIF11DGAT1RAB9ANPC1TP53 | |
| SCHEMBL7812461 | 0.76 | POLB (0.39) | KIF11DGAT1RAB9ANPC1TP53 | |
| SCHEMBL2655921 | 0.75 | NPC1 (0.64) | KIF11DGAT1RAB9ANPC1TP53 | |
| SCHEMBL22539620 | 0.75 | NPC1 (0.64) | KIF11DGAT1RAB9ANPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023121184-A1 | SUBSTITUTED THIAZOLIDINEDIONE DERIVATIVE COMPOUND, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER, COMPRISING SAME | (주)메디픽 | 2023-06-29 | — | — | WO | disclosed |