Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.60 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 3/20 | 0.43 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10154066 | 1.00 | KIF11 (0.60) | KIF11DGAT1XDHSLC22A12CA12 | |
| SCHEMBL10154177 | 0.94 | KIF11 (0.55) | KIF11DGAT1XDHSLC22A12CA12 | |
| SCHEMBL10154180 | 0.91 | KIF11 (0.51) | KIF11DGAT1XDHSLC22A12CA12 | |
| SCHEMBL23319641 | 0.86 | KIF11 (0.61) | KIF11XDHNPC1RAB9AMITF | |
| SCHEMBL4322427 | 0.86 | KIF11 (0.61) | KIF11XDHNPC1RAB9AMITF | |
| SCHEMBL25094279 | 0.86 | KIF11 (0.55) | KIF11DGAT1XDHSLC22A12CA12 | |
| SCHEMBL25754718 | 0.84 | KIF11 (0.53) | KIF11DGAT1XDHSLC22A12CA12 | |
| SCHEMBL10154078 | 0.83 | KIF11 (0.87) | KIF11XDHNPC1RAB9AALDH1A1 | |
| SCHEMBL10154062 | 0.83 | KIF11 (0.87) | KIF11XDHNPC1RAB9AALDH1A1 | |
| SCHEMBL23959634 | 0.82 | KDM4E (0.45) | KIF11XDHSLC22A12CYP1A1CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423192-A1 | METAL COMPLEX HAVING AROMATIC LIGAND THAT CONTAINS NITROGEN ATOM | Sumitomo Chemical Company, Limited (JP) | 2012-02-29 | — | — | EP | disclosed |
| US-20120041203-A1 | METAL COMPLEX HAVING AROMATIC RING LIGAND CONTAINING NITROGEN ATOM | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-02-16 | — | — | US | disclosed |
| US-20120041203-A1 | METAL COMPLEX HAVING AROMATIC RING LIGAND CONTAINING NITROGEN ATOM | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120041203-A1 | METAL COMPLEX HAVING AROMATIC RING LIGAND CONTAINING NITROGEN ATOM | MICA, CD4, CLTC | KIF11 913/4885DGAT1 4416/4885XDH 3101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.