SCHEMBL25754847

SCHEMBL25754847

CC#CC(=O)C(N)OCCOCCOCCn1ccnn1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 2/20 0.30
DPP4 P27487 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25754827 0.86 CYP19A1 (0.30) CYP19A1DPP4
SCHEMBL25754844 0.79 DPP4 (0.32) DPP4
SCHEMBL25754846 0.77 DPP4 (0.33) DPP4
SCHEMBL25755100 0.76 CYP19A1 (0.30) CYP19A1DPP4
SCHEMBL25755111 0.75 CYP19A1 (0.32) CYP19A1DPP4
SCHEMBL25754829 0.74 SLC6A2 (0.38)
SCHEMBL25755126 0.73 DPP4 (0.31) DPP4
SCHEMBL19652352 0.73 CYP19A1 (0.33) CYP19A1DPP4
SCHEMBL25754790 0.73 SLC6A2 (0.35)
SCHEMBL25755132 0.72 DPP4 (0.38) DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230210999-A1 TARGETED PROTEASE DEGRADATION (TED) PLATFORM EUBULUS BIOTHERAPEUTICS (HONG KONG) LIMITED (HK) 2023-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230210999-A1 TARGETED PROTEASE DEGRADATION (TED) PLATFORM UCHL3, UBE2L3, ADAM33 CYP19A1 2065/4885DPP4 1068/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.