Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2572975 | 0.91 | PTGDR2 (0.38) | KCNH2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL2570608 | 0.90 | KCNH2 (0.36) | KCNH2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL2570741 | 0.86 | PTGDR2 (0.44) | KCNH2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL2570443 | 0.83 | PTGDR2 (0.36) | KCNH2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL2572974 | 0.80 | PTGDR2 (0.38) | KCNH2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL533987 | 0.80 | AR (0.36) | MBOAT4 | |
| SCHEMBL2579246 | 0.78 | PTGDR2 (0.34) | PTGDR2 | |
| SCHEMBL2570549 | 0.78 | PTGDR2 (0.53) | PDE4APDE4BPDE4CPDE4DPTGDR2 | |
| SCHEMBL2580577 | 0.77 | TGFBR1 (0.30) | — | |
| SCHEMBL2579403 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2139881-B1 | QUINOLINES AND THEIR THERAPEUTIC USE | PULMAGEN THERAPEUTICS ASTHMA LTD (GB) | 2011-11-09 | — | — | EP | claimed |