Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GPR4 | P46093 | 2/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2579240 | 0.89 | PTGDR2 (0.34) | PTGDR2GPR4CYP3A4 | |
| SCHEMBL2580083 | 0.88 | GPR4 (0.32) | GPR4 | |
| SCHEMBL2570820 | 0.85 | PTGDR2 (0.50) | PTGDR2 | |
| SCHEMBL2581497 | 0.82 | KCNH2 (0.34) | — | |
| SCHEMBL2570648 | 0.82 | PTGDR2 (0.41) | PTGDR2 | |
| SCHEMBL2574521 | 0.80 | USP1 (0.32) | — | |
| SCHEMBL2576049 | 0.80 | PTGDR2 (0.37) | PTGDR2GPR4 | |
| SCHEMBL533987 | 0.80 | AR (0.36) | ALOX5 | |
| SCHEMBL2579403 | 0.79 | — | — | |
| SCHEMBL2575500 | 0.78 | KCNH2 (0.36) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2139881-B1 | QUINOLINES AND THEIR THERAPEUTIC USE | PULMAGEN THERAPEUTICS ASTHMA LTD (GB) | 2011-11-09 | — | — | EP | claimed |