Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER2 | P43116 | 3/20 | 0.39 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.35 |
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2584185 | 1.00 | PTGER2 (0.39) | PTGER2FFAR2ALDH1A1DPP4GPR119 | |
| SCHEMBL2588094 | 0.93 | FFAR2 (0.39) | FFAR2ALDH1A1DPP4GPR119HCRTR2 | |
| SCHEMBL2585262 | 0.93 | FFAR2 (0.39) | FFAR2ALDH1A1DPP4GPR119HCRTR2 | |
| SCHEMBL2587832 | 0.88 | FFAR2 (0.42) | PTGER2FFAR2ALDH1A1HCRTR2TBXA2R | |
| SCHEMBL2351859 | 0.82 | FFAR2 (0.43) | FFAR2DPP4GPR119TRPV3MMP13 | |
| SCHEMBL2588178 | 0.81 | FFAR2 (0.37) | FFAR2DPP4GPR119HCRTR2MMP13 | |
| SCHEMBL2585724 | 0.81 | FFAR2 (0.37) | FFAR2DPP4GPR119HCRTR2MMP13 | |
| SCHEMBL4501609 | 0.80 | FFAR2 (0.44) | FFAR2ALDH1A1HCRTR2 | |
| SCHEMBL2584676 | 0.80 | FFAR2 (0.44) | FFAR2ALDH1A1HCRTR2 | |
| SCHEMBL2586267 | 0.79 | FFAR2 (0.45) | FFAR2ALDH1A1DPP4GPR119MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8048878-B2 | Two cyclic cinnamide compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-11-01 | — | — | US | disclosed |