Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.32 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2588178 | 1.00 | FFAR2 (0.37) | FFAR2DPP4KDM1AHDAC8HDAC6 | |
| SCHEMBL4512679 | 0.88 | FFAR2 (0.41) | FFAR2NR1H4HCRTR2PSEN1PSEN2 | |
| SCHEMBL4512672 | 0.88 | FFAR2 (0.41) | FFAR2NR1H4HCRTR2PSEN1PSEN2 | |
| SCHEMBL4501421 | 0.88 | FFAR2 (0.41) | FFAR2NR1H4HCRTR2PSEN1PSEN2 | |
| SCHEMBL4501426 | 0.88 | FFAR2 (0.41) | FFAR2NR1H4HCRTR2PSEN1PSEN2 | |
| SCHEMBL2588094 | 0.83 | FFAR2 (0.39) | FFAR2DPP4MMP13HCRTR2GPR119 | |
| SCHEMBL2585262 | 0.83 | FFAR2 (0.39) | FFAR2DPP4MMP13HCRTR2GPR119 | |
| SCHEMBL2581640 | 0.82 | FFAR2 (0.39) | FFAR2DPP4KDM1AHDAC8HDAC6 | |
| SCHEMBL2584569 | 0.82 | FFAR2 (0.39) | FFAR2DPP4KDM1AHDAC8HDAC6 | |
| SCHEMBL2584185 | 0.81 | PTGER2 (0.39) | FFAR2DPP4MMP13HCRTR2GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8048878-B2 | Two cyclic cinnamide compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-11-01 | — | — | US | disclosed |