SCHEMBL25755071

SCHEMBL25755071

CNC(=O)CCOCCC(N)CCn1ccnn1

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.39
PADI4 Q9UM07 2/20 0.35
HDAC1 Q13547 1/20 0.32
CYP19A1 P11511 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25755061 0.86 DPP4 (0.34) DPP4PADI4CYP19A1
SCHEMBL25755073 0.82 CYP19A1 (0.34) HDAC1CYP19A1
SCHEMBL25755072 0.82 DPP4 (0.39) DPP4PADI4
SCHEMBL25754814 0.82 DPP4 (0.34) DPP4PADI4
SCHEMBL25755066 0.82 PADI4 (0.33) DPP4PADI4HDAC1CYP19A1
SCHEMBL25755132 0.81 DPP4 (0.38) DPP4PADI4
SCHEMBL25754811 0.81 SLC6A2 (0.34) DPP4PADI4HDAC1
SCHEMBL25755064 0.80 DPP4 (0.32) DPP4PADI4
SCHEMBL25755078 0.77 PADI4 (0.33) DPP4PADI4CYP19A1
SCHEMBL25754773 0.76 SLC6A2 (0.36) HDAC1CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230210999-A1 TARGETED PROTEASE DEGRADATION (TED) PLATFORM EUBULUS BIOTHERAPEUTICS (HONG KONG) LIMITED (HK) 2023-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230210999-A1 TARGETED PROTEASE DEGRADATION (TED) PLATFORM UCHL3, UBE2L3, ADAM33 DPP4 1068/4885PADI4 1134/4885HDAC1 596/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.