Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 6/20 | 0.46 |
| ▸ | SCN10A | Q9Y5Y9 | 5/20 | 0.45 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.41 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.40 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.40 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.40 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.40 |
| ▸ | ATP1A2 | P50993 | 1/20 | 0.40 |
| ▸ | ATP1B3 | P54709 | 1/20 | 0.40 |
| ▸ | FXYD2 | P54710 | 1/20 | 0.40 |
| ▸ | ATP1A4 | Q13733 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12356693 | 0.82 | HRH4 (0.41) | SCN5ASCN10AAAK1SCN9ADYRK1A | |
| SCHEMBL14063532 | 0.81 | DYRK1A (0.62) | AAK1ABL1DYRK1A | |
| SCHEMBL25754727 | 0.80 | DYRK1A (0.65) | SCN5ASCN10ASCN9AABL1DYRK1A | |
| SCHEMBL29421422 | 0.77 | SCN9A (0.62) | SCN9A | |
| SCHEMBL29421413 | 0.77 | SCN9A (0.62) | SCN9A | |
| SCHEMBL17341047 | 0.77 | MAPK10 (0.43) | — | |
| SCHEMBL1229896 | 0.76 | SCN5A (0.49) | SCN5ASCN9AABL1DYRK1ANISCH | |
| SCHEMBL13741332 | 0.76 | SCN5A (0.49) | SCN5ASCN9AABL1DYRK1AKIF11 | |
| SCHEMBL28043073 | 0.76 | SCN5A (0.46) | SCN5ASCN10ASCN9AABL1DYRK1A | |
| SCHEMBL17773153 | 0.75 | MAPT (0.46) | AAK1DYRK1AKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023121184-A1 | SUBSTITUTED THIAZOLIDINEDIONE DERIVATIVE COMPOUND, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER, COMPRISING SAME | (주)메디픽 | 2023-06-29 | — | — | WO | disclosed |