Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 3/20 | 0.46 |
| ▸ | ABL1 | P00519 | 2/20 | 0.44 |
| ▸ | BCR | P11274 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | FDPS | P14324 | 2/20 | 0.42 |
| ▸ | GSK3B | P49841 | 3/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | RAF1 | P04049 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | WNT3A | P56704 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | GPR39 | O43194 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23763117 | 0.82 | RXRA (0.43) | ABL1BCRRAF1EPHX2GPR39 | |
| SCHEMBL28043122 | 0.80 | KIF11 (0.53) | ABL1BCRKIF11GSK3BGSK3A | |
| SCHEMBL25754727 | 0.80 | DYRK1A (0.65) | SCN5AABL1SCN9AKIF11SCN10A | |
| SCHEMBL4325626 | 0.79 | MAPK10 (0.68) | ABL1BCRGSK3B | |
| SCHEMBL28266489 | 0.77 | GSK3B (0.64) | ABL1GSK3BGSK3A | |
| SCHEMBL6530522 | 0.77 | MAPK10 (0.61) | — | |
| Hydrochloric Acid SCHEMBL28074538 | 0.77 | ABL1 (0.61) | ABL1BCRADORA3 | |
| SCHEMBL1229896 | 0.76 | SCN5A (0.49) | SCN5AABL1BCRSCN9ADYRK1A | |
| SCHEMBL13741332 | 0.76 | SCN5A (0.49) | SCN5AABL1BCRSCN9AKIF11 | |
| SCHEMBL25755093 | 0.76 | SCN5A (0.46) | SCN5AABL1SCN9AKIF11SCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105143188-A | Novel sulfonamide trpa1 receptor antagonists | PHARMESTE S R L IN LIQUIDATION | 2015-12-09 | — | — | CN | disclosed |