Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.65 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.53 |
| ▸ | WNT3A | P56704 | 1/20 | 0.53 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.49 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.46 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.46 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.46 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.46 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.46 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.46 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27859569 | 0.89 | DYRK1A (0.52) | DYRK1AGRM2WNT3ASCN5APSEN1 | |
| SCHEMBL17396830 | 0.84 | DYRK1A (0.62) | DYRK1AGRM2WNT3ACYP2D6CYP2C9 | |
| SCHEMBL12368117 | 0.80 | DYRK1A (0.45) | DYRK1AGRM2WNT3ASCN5ACYP2D6 | |
| SCHEMBL31729856 | 0.80 | DYRK1A (0.45) | DYRK1AGRM2WNT3APSEN1PSEN2 | |
| SCHEMBL13741332 | 0.80 | SCN5A (0.49) | DYRK1ASCN5ASCN9AABL1KIF11 | |
| SCHEMBL1229896 | 0.80 | SCN5A (0.49) | DYRK1ASCN5AKCNH2SCN9AABL1 | |
| SCHEMBL2185201 | 0.80 | WNT3A (0.71) | WNT3APSEN1PSEN2APH1BNCSTN | |
| SCHEMBL28043073 | 0.80 | SCN5A (0.46) | DYRK1AWNT3ASCN5ASCN10ASCN9A | |
| SCHEMBL25755093 | 0.80 | SCN5A (0.46) | DYRK1ASCN5AKCNH2SCN10ASCN9A | |
| SCHEMBL4084384 | 0.79 | DYRK1A (1.00) | DYRK1AWNT3APSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023121184-A1 | SUBSTITUTED THIAZOLIDINEDIONE DERIVATIVE COMPOUND, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER, COMPRISING SAME | (주)메디픽 | 2023-06-29 | — | — | WO | disclosed |