SCHEMBL25755293

SCHEMBL25755293

CCCCCCCC(=O)c1cccc(C=O)c1

nearest known ligand 0.66

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
UNG P13051 1/20 0.51
HSD17B3 P37058 6/20 0.51
MAPT P10636 2/20 0.50
MEN1 O00255 1/20 0.50
ALDH1A1 P00352 1/20 0.50
HTT P42858 1/20 0.50
KMT2A Q03164 1/20 0.50
ATM Q13315 1/20 0.50
L3MBTL1 Q9Y468 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
LMNA P02545 2/20 0.47
THRA P10827 1/20 0.47
THRB P10828 1/20 0.47
CES2 O00748 2/20 0.46
CES1 P23141 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL95049 0.87 UNG (0.58) UNGHSD17B3MAPTMEN1ALDH1A1
SCHEMBL13085731 0.85 HSD17B3 (0.62) HSD17B3MAPTMEN1ALDH1A1HTT
SCHEMBL3845268 0.85 HDAC3 (0.46) HSD17B3MAPTMEN1ALDH1A1HTT
SCHEMBL10660121 0.84 L3MBTL1 (0.50) HSD17B3MAPTL3MBTL1TDP1LMNA
SCHEMBL10661451 0.84 L3MBTL1 (0.50) HSD17B3MAPTL3MBTL1TDP1LMNA
SCHEMBL10660126 0.84 L3MBTL1 (0.50) HSD17B3MAPTL3MBTL1TDP1LMNA
SCHEMBL9506499 0.81 HSD17B3 (0.67) HSD17B3MAPTL3MBTL1TDP1LMNA
SCHEMBL3844202 0.81 HSD17B3 (0.67) HSD17B3MAPTL3MBTL1TDP1LMNA
SCHEMBL6839650 0.81 HSD17B3 (0.67) HSD17B3MAPTL3MBTL1TDP1LMNA
SCHEMBL11597037 0.80 HSD17B3 (0.56) HSD17B3MAPTMEN1ALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023110947-A1 PROCESS FOR LIGHTENING OR FOR SIMULTANEOUSLY BLEACHING AND DYEING KERATIN FIBRES L'OREAL (FR) 2023-06-22 WO disclosed