SCHEMBL25755871

SCHEMBL25755871

COc1cc(CCOC(=O)[C@@H]2CCCCN2C(O)OCc2ccccc2)cc(OC)c1OC

nearest known ligand 0.59

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FKBP1A P62942 18/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25755801 1.00 FKBP1A (0.59) FKBP1A
SCHEMBL25755557 0.84 FKBP1A (0.51) FKBP1A
SCHEMBL21241601 0.83 FKBP1A (0.61) FKBP1A
SCHEMBL21241503 0.83 FKBP1A (0.61) FKBP1A
SCHEMBL25756833 0.83 FKBP1A (0.60) FKBP1A
SCHEMBL21241447 0.81 FKBP1A (0.59) FKBP1A
SCHEMBL25756049 0.81 FKBP1A (0.59) FKBP1A
SCHEMBL21241599 0.78 FKBP1A (0.69) FKBP1A
SCHEMBL21241498 0.78 FKBP1A (0.69) FKBP1A
SCHEMBL25755869 0.78 FKBP1A (0.68) FKBP1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3746440-B1 PIPECOLIC ESTERS FOR INHIBITION OF THE PROTEASOME UNIV TEXAS (US) 2023-07-05 EP disclosed