SCHEMBL25756059

SCHEMBL25756059

C#CCCN(CCOCCOCCO)C(=O)OC(C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CA14 Q9ULX7 1/20 0.38
SSTR4 P31391 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
CSNK2A2 P19784 1/20 0.30
CSNK2A1 P68400 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25032343 1.00 CA14 (0.38) CA14SSTR4MEN1KMT2ACSNK2A2
SCHEMBL25032171 0.89 CA14 (0.35) CA14
SCHEMBL19437619 0.88 CA14 (0.45) CA14SSTR4MEN1KMT2ACSNK2A2
SCHEMBL31584056 0.88 CA14 (0.45) CA14SSTR4MEN1KMT2ACSNK2A2
SCHEMBL31618313 0.88 CA14 (0.45) CA14SSTR4MEN1KMT2ACSNK2A2
SCHEMBL23296185 0.87 CA14 (0.46) CA14SSTR4MEN1KMT2ACSNK2A2
SCHEMBL15295661 0.85 CA14 (0.43) CA14SSTR4
SCHEMBL25031989 0.85 CA14 (0.43) CA14SSTR4
SCHEMBL25756127 0.84 CA14 (0.36) CA14
SCHEMBL25032083 0.84 CA14 (0.36) CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230210999-A1 TARGETED PROTEASE DEGRADATION (TED) PLATFORM EUBULUS BIOTHERAPEUTICS (HONG KONG) LIMITED (HK) 2023-07-06 US disclosed
US-20230210999-A1 TARGETED PROTEASE DEGRADATION (TED) PLATFORM EUBULUS BIOTHERAPEUTICS (HONG KONG) LIMITED (HK) 2023-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230210999-A1 TARGETED PROTEASE DEGRADATION (TED) PLATFORM UCHL3, UBE2L3, ADAM33 CA14 2124/4885SSTR4 3617/4885MEN1 940/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.