Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 14/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | STAT3 | P40763 | 1/20 | 0.51 |
| ▸ | BRD4 | O60885 | 4/20 | 0.50 |
| ▸ | TNF | P01375 | 1/20 | 0.50 |
| ▸ | IL1B | P01584 | 1/20 | 0.50 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.50 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.50 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.50 |
| ▸ | MAP1LC3B | Q9GZQ8 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20913661 | 0.96 | CRBN (0.55) | CRBNHDAC3HDAC1STAT3BRD4 | |
| SCHEMBL19438857 | 0.96 | CRBN (0.55) | CRBNHDAC3HDAC1STAT3BRD4 | |
| SCHEMBL19438825 | 0.96 | CRBN (0.55) | CRBNHDAC3HDAC1STAT3BRD4 | |
| SCHEMBL30577345 | 0.96 | CRBN (0.55) | CRBNHDAC3HDAC1STAT3BRD4 | |
| SCHEMBL23772826 | 0.93 | CRBN (0.55) | CRBNHDAC3HDAC1STAT3BRD4 | |
| SCHEMBL17821424 | 0.93 | CRBN (0.55) | CRBNHDAC3HDAC1STAT3BRD4 | |
| SCHEMBL20913681 | 0.93 | CRBN (0.55) | CRBNHDAC3HDAC1STAT3BRD4 | |
| SCHEMBL24068471 | 0.92 | STAT3 (0.54) | CRBNHDAC3HDAC1STAT3BRD4 | |
| SCHEMBL25032251 | 0.91 | STAT3 (0.52) | CRBNHDAC3HDAC1STAT3BRD4 | |
| SCHEMBL24778362 | 0.91 | CRBN (0.57) | CRBNHDAC3HDAC1STAT3BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230210999-A1 | TARGETED PROTEASE DEGRADATION (TED) PLATFORM | EUBULUS BIOTHERAPEUTICS (HONG KONG) LIMITED (HK) | 2023-07-06 | — | — | US | disclosed |
| US-20230210999-A1 | TARGETED PROTEASE DEGRADATION (TED) PLATFORM | EUBULUS BIOTHERAPEUTICS (HONG KONG) LIMITED (HK) | 2023-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230210999-A1 | TARGETED PROTEASE DEGRADATION (TED) PLATFORM | UCHL3, UBE2L3, ADAM33 | CRBN 286/4885HDAC3 739/4885HDAC1 596/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.