Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.35 |
| ▸ | PDE4A | P27815 | 3/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | PI4KA | P42356 | 1/20 | 0.34 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.34 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 2/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 2/20 | 0.32 |
| ▸ | GSK3B | P49841 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27199385 | 0.83 | RAB9A (0.36) | RAB9AADORA2APDE4APDE4BPDE4C | |
| Hydrochloric Acid SCHEMBL27199482 | 0.82 | ADORA2B (0.33) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL27199465 | 0.78 | PDE4A (0.35) | RAB9AADORA2APDE4APDE4BPDE4C | |
| Hydrochloric Acid SCHEMBL27199695 | 0.74 | KDM4E (0.32) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL27199518 | 0.72 | KDM4E (0.33) | TSHRSMN1; SMN2 | |
| SCHEMBL15265817 | 0.69 | ADORA2B (0.33) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL20709994 | 0.69 | ADORA2B (0.42) | RAB9AADORA2APDE4APDE4BPDE4C | |
| SCHEMBL25665462 | 0.68 | PDE4A (0.41) | RAB9AADORA2APDE4APDE4BPDE4C | |
| SCHEMBL16444440 | 0.65 | TSHR (0.44) | RAB9AADORA2BTSHRSMN1; SMN2BRD4 | |
| SCHEMBL25665468 | 0.65 | ADORA2B (0.41) | RAB9AADORA2APDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109954-A1 | TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF | LYNK PHARMACEUTICALS CO. LTD. (CN) | 2023-06-22 | — | — | WO | disclosed |