Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A2 | P31639 | 8/20 | 0.37 |
| ▸ | HTR2C | P28335 | 3/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD5 | P21918 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14605468 | 0.78 | SLC5A2 (0.49) | SLC5A2HTR2CHTR2ASLC6A4HTR2B | |
| SCHEMBL13969632 | 0.78 | SLC5A2 (0.49) | SLC5A2HTR2CHTR2ASLC6A4HTR2B | |
| SCHEMBL26764732 | 0.77 | SLC5A2 (0.57) | SLC5A2SLC5A1 | |
| SCHEMBL21600643 | 0.72 | HTR2C (0.49) | HTR2CHTR2ASLC6A4HTR2BSLC6A3 | |
| SCHEMBL25757174 | 0.71 | SLC5A2 (0.42) | SLC5A2HTR2CHTR2ASLC6A4HTR2B | |
| SCHEMBL22200140 | 0.71 | SLC5A2 (0.43) | SLC5A2HTR2CHTR2AHTR2BSLC5A1 | |
| SCHEMBL1964991 | 0.69 | MEN1 (0.38) | SLC5A2HTR2CHTR2ASLC6A4HTR2B | |
| SCHEMBL13885909 | 0.64 | MANBA (0.37) | — | |
| SCHEMBL1499496 | 0.64 | TSHR (0.54) | HTR2CHTR2ASLC6A4HTR2BSLC6A3 | |
| SCHEMBL7779276 | 0.64 | TSHR (0.54) | HTR2CHTR2ASLC6A4HTR2BSLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4206212-A1 | SGLT-2 INHIBITOR SARCOSINE CO-CRYSTAL, PREPARATION METHOD THEREFOR AND USE THEREOF | Beijing Creatron Institute of Pharmaceutical Research Co., Ltd. (CN) | 2023-07-05 | — | — | EP | disclosed |