Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 3/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HPN | P05981 | 1/20 | 0.41 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6481069 | 1.00 | TSHR (0.54) | TSHRPARP1HTR2CHTR2ASLC6A4 | |
| SCHEMBL1499496 | 1.00 | TSHR (0.54) | TSHRPARP1HTR2CHTR2ASLC6A4 | |
| SCHEMBL7815997 | 0.85 | HTR2C (0.41) | TSHRPARP1HTR2CHTR2ASLC6A4 | |
| SCHEMBL21974861 | 0.84 | TSHR (0.67) | TSHRPARP1MEN1KMT2AGSTO1 | |
| SCHEMBL46283 | 0.84 | TSHR (0.67) | TSHRPARP1MEN1KMT2AGSTO1 | |
| SCHEMBL12186571 | 0.81 | DRD2 (0.50) | TSHRPARP1HTR2CHTR2ASLC6A4 | |
| SCHEMBL12186575 | 0.81 | DRD2 (0.50) | TSHRPARP1HTR2CHTR2ASLC6A4 | |
| SCHEMBL15154742 | 0.81 | DRD2 (0.50) | TSHRPARP1HTR2CHTR2ASLC6A4 | |
| SCHEMBL2599491 | 0.81 | DRD2 (0.50) | TSHRPARP1HTR2CHTR2ASLC6A4 | |
| SCHEMBL15154774 | 0.81 | DRD2 (0.50) | TSHRPARP1HTR2CHTR2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115927276-A | Halogen alcohol dehalogenase mutant and application thereof in synthesizing chiral oxazolidinone | 中国科学院天津工业生物技术研究所 | 2023-04-07 | — | — | CN | claimed |
| EP-0735142-B1 | Process for producing (R)-styrene oxides | SUMIKA FINE CHEMICALS CO LTD (JP) | 2001-10-24 | — | — | EP | claimed |
| US-5717116-A | TREATING A MIXTURE OF PHENYLHALOGENOMETHYLCARBINOLS WITH A LIPASE IN THE PRESENCE OF A CARBOXYLATE FOLLOWED BY CYCLIZATION WITH A BASE | SUMIKA FINE CHEMICALS COMPANY, LIMITED (JP) | 1998-02-10 | — | — | US | claimed |
| EP-0735142-A2 | Process for producing (R)-styrene oxides | SUMIKA FINE CHEMICAL COMPANY, LTD. (JP) | 1996-10-02 | — | — | EP | claimed |
| CN-115927276-B | Halohydrin dehalogenase mutant and application thereof in synthesis of chiral oxazolidinone | 中国科学院天津工业生物技术研究所 | 2024-08-27 | — | — | CN | disclosed |
| CN-115927276-A | Halogen alcohol dehalogenase mutant and application thereof in synthesizing chiral oxazolidinone | 中国科学院天津工业生物技术研究所 | 2023-04-07 | — | — | CN | disclosed |
| US-5658904-A | COGNITION ACTIVATORS; BRAIN DISORDERS; ALZHEIMER*S DISEASE | TOYAMA CHEMICAL CO., LTD. (JP) | 1997-08-19 | — | — | US | disclosed |
| US-5612381-A | 1,2-ethanediol derivative and salt thereof process for producing the same, and cerebral function-improving agent comprising the same | TOYAMA CHEMICAL CO., LTD. (JP) | 1997-03-18 | — | — | US | disclosed |