Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD5 | P21918 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.35 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.34 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14602807 | 0.73 | HTR2C (0.68) | HTR2CHTR2ASLC6A4HTR2BSLC6A3 | |
| SCHEMBL8331072 | 0.73 | HTR2C (0.47) | HTR2CHTR2ASLC6A4HTR2BSLC6A3 | |
| SCHEMBL25757049 | 0.72 | SLC5A2 (0.37) | HTR2CHTR2ASLC6A4HTR2BSLC6A3 | |
| SCHEMBL8331608 | 0.71 | HTR2A (0.45) | HTR2CHTR2ASLC6A4HTR2BSLC6A3 | |
| SCHEMBL8331728 | 0.71 | ALOX5 (0.46) | HTR2CHTR2ASLC6A4HTR2BSLC6A3 | |
| SCHEMBL26764732 | 0.69 | SLC5A2 (0.57) | — | |
| SCHEMBL7092556 | 0.69 | HTR2C (0.61) | HTR2CHTR2ASLC6A4HTR2BSLC6A3 | |
| SCHEMBL7002711 | 0.69 | HTR2C (0.61) | HTR2CHTR2ASLC6A4HTR2BSLC6A3 | |
| SCHEMBL7002709 | 0.69 | HTR2C (0.61) | HTR2CHTR2ASLC6A4HTR2BSLC6A3 | |
| SCHEMBL18533592 | 0.68 | SMN1; SMN2 (0.42) | HTR2CHTR2AHTR2BSLC6A3DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2435407-B1 | ARYL SUBSTITUTED CARBOXAMIDE DERIVATIVES AS CALCIUM OR SODIUM CHANNEL BLOCKERS | RAQUALIA PHARMA INC (JP) | 2019-12-25 | — | — | EP | disclosed |