Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | RAF1 | P04049 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | GALK1 | P51570 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25757053 | 0.77 | CNR1 (0.34) | MAPTKDM4EMEN1HTTKMT2A | |
| SCHEMBL27199578 | 0.72 | JAK1 (0.35) | ADORA2AADORA2B | |
| SCHEMBL27199384 | 0.72 | KDM4E (0.33) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL27199496 | 0.70 | CNR1 (0.35) | MAPTKDM4EMEN1HTTKMT2A | |
| SCHEMBL25757051 | 0.67 | RXFP1 (0.33) | KDM4EADORA2AADORA2B | |
| SCHEMBL2429551 | 0.67 | NOS2 (0.35) | EGFRADORA2AADORA2B | |
| SCHEMBL25670290 | 0.66 | BRD4 (0.34) | MAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL15833034 | 0.66 | ALDH1A1 (0.44) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL25756717 | 0.64 | ALDH1A1 (0.35) | KDM4EALDH1A1ADORA2AADORA2B | |
| SCHEMBL15792310 | 0.62 | ADORA2A (0.44) | MAPTKDM4EMEN1ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109954-A1 | TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF | LYNK PHARMACEUTICALS CO. LTD. (CN) | 2023-06-22 | — | — | WO | disclosed |