Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16623570 | 0.75 | PARP1 (0.31) | PARP1 | |
| SCHEMBL31701620 | 0.70 | CYP1A2 (0.35) | PARP1ROCK2 | |
| SCHEMBL31701724 | 0.68 | PARP1 (0.33) | PARP1ROCK2 | |
| SCHEMBL22216142 | 0.68 | TSHR (0.33) | — | |
| SCHEMBL17849234 | 0.66 | JAK2 (0.38) | ROCK2 | |
| SCHEMBL31700720 | 0.66 | KDM4E (0.35) | PARP1EGFR | |
| SCHEMBL25757086 | 0.65 | CRBN (0.34) | — | |
| SCHEMBL10094591 | 0.63 | — | — | |
| SCHEMBL3652772 | 0.61 | NAPRT (0.41) | PARP1ROCK2EGFR | |
| SCHEMBL3649191 | 0.61 | KDM4E (0.41) | PARP1ROCK2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109954-A1 | TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF | LYNK PHARMACEUTICALS CO. LTD. (CN) | 2023-06-22 | — | — | WO | disclosed |