Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14467741 | 0.68 | IDH1 (0.44) | KDM4EALDH1A1MAPK1 | |
| SCHEMBL12417619 | 0.66 | BRD4 (0.38) | KDM4EALDH1A1 | |
| SCHEMBL25757085 | 0.65 | PARP1 (0.32) | — | |
| SCHEMBL1399812 | 0.62 | CA12 (0.50) | KDM4EALDH1A1 | |
| SCHEMBL14625069 | 0.62 | RAB9A (0.34) | KDM4EALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL17594820 | 0.61 | CA12 (0.39) | KDM4EALDH1A1MAPK1 | |
| SCHEMBL27305850 | 0.60 | LIPG (0.38) | CRBNKDM4EALDH1A1 | |
| SCHEMBL17029567 | 0.60 | HDAC8 (0.32) | KDM4EALDH1A1MAPK1 | |
| SCHEMBL23839890 | 0.59 | GABRA1 (0.45) | KDM4EALDH1A1MAPK1 | |
| SCHEMBL24019687 | 0.58 | IDH1 (0.44) | KDM4EALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109954-A1 | TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF | LYNK PHARMACEUTICALS CO. LTD. (CN) | 2023-06-22 | — | — | WO | disclosed |