SCHEMBL22216142

SCHEMBL22216142

CNc1cc[nH]c(=O)c1C=N

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33
BLM P54132 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31701620 0.72 CYP1A2 (0.35) TSHRBLM
SCHEMBL22216321 0.71 AURKA (0.43)
SCHEMBL31701724 0.71 PARP1 (0.33)
SCHEMBL31700720 0.68 KDM4E (0.35)
SCHEMBL25757085 0.68 PARP1 (0.32)
SCHEMBL10094591 0.66
SCHEMBL25057453 0.66 PDPK1 (0.38) TSHRBLM
SCHEMBL22146244 0.63 JAK2 (0.37)
SCHEMBL19657808 0.63
SCHEMBL19122583 0.63 KEAP1 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3892621-A1 HALOALLYLAMINE COMPOUNDS AND APPLICATION THEREOF Nanjing Transthera Biosciences Co., Ltd. (CN) 2021-10-13 EP disclosed
WO-2020143763-A1 HALOALLYLAMINE COMPOUNDS AND APPLICATION THEREOF 南京药捷安康生物科技有限公司 2020-07-16 WO disclosed