Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 2/20 | 0.37 |
| ▸ | APLNR | P35414 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 10/20 | 0.37 |
| ▸ | CTSS | P25774 | 8/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9825794 | 0.82 | CA1 (0.38) | CA1CA2CA7KMT2AMEN1 | |
| SCHEMBL15203812 | 0.82 | CA1 (0.38) | CA1CA2CA7KMT2AMEN1 | |
| SCHEMBL10733759 | 0.82 | CA1 (0.38) | CA1CA2CA7KMT2AMEN1 | |
| SCHEMBL2377942 | 0.81 | CA1 (0.40) | CA1CA2CA7KMT2AMEN1 | |
| SCHEMBL9509419 | 0.81 | CA1 (0.40) | CA1CA2CA7KMT2AMEN1 | |
| SCHEMBL15105955 | 0.81 | CA1 (0.40) | CA1CA2CA7KMT2AMEN1 | |
| SCHEMBL2377936 | 0.81 | CA1 (0.40) | CA1CA2CA7KMT2AMEN1 | |
| SCHEMBL23177048 | 0.81 | KMT2A (0.40) | CA1CA2CA7KMT2AMEN1 | |
| SCHEMBL3450579 | 0.81 | CTSK (0.38) | CA1CA2CA7KMT2AMEN1 | |
| SCHEMBL2377966 | 0.81 | CA1 (0.37) | CA1CA2CA7KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109926-A1 | SPIROOXINDOLE COMPOUND AND USE THEREOF IN PREPARATION OF PROTEASE INHIBITOR AS ANTIVIRAL DRUG | 南京药石科技股份有限公司 | 2023-06-22 | — | — | WO | disclosed |