Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | APLNR | P35414 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 2/20 | 0.38 |
| ▸ | CTSK | P43235 | 9/20 | 0.38 |
| ▸ | CTSS | P25774 | 6/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15105955 | 0.83 | CA1 (0.40) | CA1CA2CA7KMT2AMEN1 | |
| SCHEMBL2377942 | 0.83 | CA1 (0.40) | CA1CA2CA7KMT2AMEN1 | |
| SCHEMBL16057398 | 0.83 | CA1 (0.44) | CA1CA2CA7KMT2AMEN1 | |
| SCHEMBL2377936 | 0.83 | CA1 (0.40) | CA1CA2CA7KMT2AMEN1 | |
| SCHEMBL14216682 | 0.82 | CA1 (0.35) | CA1CA2CA7KMT2AMEN1 | |
| SCHEMBL14899016 | 0.82 | CA1 (0.35) | CA1CA2CA7KMT2AMEN1 | |
| SCHEMBL31374987 | 0.81 | CA1 (0.39) | CA1CA2CA7KMT2AMEN1 | |
| SCHEMBL28269476 | 0.81 | CA1 (0.39) | CA1CA2CA7KMT2AMEN1 | |
| SCHEMBL1480407 | 0.81 | CA1 (0.39) | CA1CA2CA7KMT2AMEN1 | |
| SCHEMBL25757600 | 0.81 | CA1 (0.39) | CA1CA2CA7KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0363994-B1 | (2R,3S,4S)-ALPHA-(CARBOXYCYCLOPROPYL)GLYCINE | SUNTORY LIMITED (JP) | 1993-09-22 | — | — | EP | disclosed |
| US-5068412-A | Nervous system disorders such as treatment of epilepsy or Huntington's chorea | SUNTORY LIMITED (JP) | 1991-11-26 | — | — | US | disclosed |