Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 3/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.40 |
| ▸ | PIM1 | P11309 | 2/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.40 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.40 |
| ▸ | LTK | P29376 | 1/20 | 0.36 |
| ▸ | MST1R | Q04912 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.33 |
| ▸ | PLK4 | O00444 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | PRKCG | P05129 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16335317 | 0.74 | DYRK1A (0.40) | DYRK1ACLK4CDK5PIM1ROCK1 | |
| SCHEMBL16535812 | 0.69 | LMNA (0.53) | DYRK1ACLK4CDK5PIM1ROCK1 | |
| SCHEMBL28730418 | 0.68 | NOTUM (0.42) | — | |
| SCHEMBL25757654 | 0.68 | CLK4 (0.42) | DYRK1ACLK4CDK5PIM1ROCK1 | |
| SCHEMBL10054248 | 0.67 | HTR2A (0.39) | DYRK1A | |
| SCHEMBL24466337 | 0.63 | CDK5 (0.46) | DYRK1ACLK4CDK5PIM1ROCK1 | |
| SCHEMBL31264207 | 0.63 | CDK5 (0.46) | DYRK1ACLK4CDK5PIM1ROCK1 | |
| SCHEMBL15566157 | 0.63 | CLK4 (0.46) | DYRK1ACLK4CDK5PIM1ROCK1 | |
| SCHEMBL16921409 | 0.63 | CDK5 (0.46) | DYRK1ACLK4CDK5PIM1ROCK1 | |
| SCHEMBL30842095 | 0.63 | CDK5 (0.46) | DYRK1ACLK4CDK5PIM1ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023098880-A1 | FUSED RING DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 上海翰森生物医药科技有限公司 | 2023-06-08 | — | — | WO | disclosed |