Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.36 |
| ▸ | FEN1 | P39748 | 4/20 | 0.36 |
| ▸ | SMPD3 | Q9NY59 | 5/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27199426 | 0.98 | NPBWR1 (0.38) | NPBWR1MCHR1ALOX5APFEN1SMPD3 | |
| SCHEMBL25759121 | 0.81 | SMPD3 (0.35) | SMPD3HTR2CALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL27199529 | 0.80 | SMPD3 (0.34) | SMPD3ALDH1A1MAPT | |
| SCHEMBL25757143 | 0.80 | SMPD3 (0.37) | SMPD3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27199419 | 0.78 | SMPD3 (0.36) | ALOX5APFEN1SMPD3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27199541 | 0.77 | GAA (0.40) | NPBWR1MCHR1SMPD3HTR2CALDH1A1 | |
| SCHEMBL27199546 | 0.76 | NPBWR1 (0.33) | NPBWR1MCHR1SMPD3HTR2CALDH1A1 | |
| SCHEMBL25754050 | 0.75 | MAP2K1 (0.39) | NPBWR1MCHR1ALDH1A1 | |
| SCHEMBL25756945 | 0.74 | DHFR (0.38) | HTR2CALDH1A1 | |
| SCHEMBL31280832 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109954-A1 | TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF | LYNK PHARMACEUTICALS CO. LTD. (CN) | 2023-06-22 | — | — | WO | disclosed |