Sugi Predict

Sugi Predict / Compounds / SCHEMBL25758089

SCHEMBL25758089

SCHEMBL25758089

Cc1cn([C@H]2C[C@@H](O)C(/C=C/P(=O)(OCOC(=O)C(C)(C)C)OCOC(=O)C(C)(C)C)O2)c(=O)[nH]c1=O

nearest known ligand 0.51

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ TK1 P04183 8/20 0.48
▸ POLB P06746 1/20 0.48
▸ TYMS P04818 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24059170 1.00 TK1 (0.48) TK1POLBTYMS
SCHEMBL24059175 0.94 TK1 (0.44) TK1POLBTYMS
SCHEMBL24059171 0.87 TK1 (0.43) TK1POLB
SCHEMBL24059188 0.86 TK1 (0.60) TK1POLBTYMS
SCHEMBL31556060 0.86 TK1 (0.60) TK1POLBTYMS
SCHEMBL24059297 0.86 TK1 (0.60) TK1POLBTYMS
SCHEMBL22111998 0.84 TK1 (0.62) TK1POLB
SCHEMBL22021811 0.84 TK1 (0.62) TK1POLB
SCHEMBL22021036 0.84 TK1 (0.62) TK1POLB
SCHEMBL24233023 0.84 TK1 (0.62) TK1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230203484-A1 DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO WAVE LIFE SCIENCES LTD. (SG) 2023-06-29 — — US disclosed