Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24233023 | 1.00 | TK1 (0.62) | TK1POLB | |
| SCHEMBL22021811 | 1.00 | TK1 (0.62) | TK1POLB | |
| SCHEMBL22021036 | 1.00 | TK1 (0.62) | TK1POLB | |
| SCHEMBL24059297 | 0.90 | TK1 (0.60) | TK1POLB | |
| SCHEMBL24059188 | 0.90 | TK1 (0.60) | TK1POLB | |
| SCHEMBL31556060 | 0.90 | TK1 (0.60) | TK1POLB | |
| SCHEMBL25752645 | 0.89 | TK1 (0.58) | TK1POLB | |
| SCHEMBL25752265 | 0.89 | TK1 (0.58) | TK1POLB | |
| SCHEMBL19255421 | 0.84 | TK1 (0.47) | TK1POLB | |
| SCHEMBL24059170 | 0.84 | TK1 (0.48) | TK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200190515-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2020-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200190515-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | RNASE1, RNASEH1, RNASEL | TK1 474/4885POLB 546/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.