Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | CFD | P00746 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25759259 | 0.94 | HRH4 (0.53) | HRH4KMT2AMEN1RCE1FLT3 | |
| SCHEMBL24112948 | 0.88 | HRH4 (0.52) | HRH4KMT2AMEN1RCE1FLT3 | |
| SCHEMBL25759251 | 0.88 | HRH4 (0.53) | HRH4KMT2AMEN1RCE1FLT3 | |
| SCHEMBL25759304 | 0.87 | HRH4 (0.49) | HRH4KMT2AMEN1RCE1FLT3 | |
| SCHEMBL25759303 | 0.86 | HRH4 (0.50) | HRH4KMT2AMEN1RCE1FLT3 | |
| SCHEMBL25759308 | 0.85 | HRH4 (0.53) | HRH4KMT2AMEN1RCE1FLT3 | |
| SCHEMBL25759248 | 0.85 | HRH4 (0.53) | HRH4KMT2AMEN1RCE1FLT3 | |
| SCHEMBL25759379 | 0.84 | HRH4 (0.50) | HRH4KMT2AMEN1RCE1FLT3 | |
| SCHEMBL25759253 | 0.84 | HRH4 (0.52) | HRH4KMT2AMEN1RCE1FLT3 | |
| SCHEMBL25759291 | 0.83 | HRH4 (0.51) | HRH4KMT2AMEN1RCE1FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230212152-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | Pardes Biosciences, Inc. | 2023-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230212152-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | CTRL, CTSL, CTSV | HRH4 4259/4885KMT2A 3383/4885MEN1 4306/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.