SCHEMBL25759640

SCHEMBL25759640

CNCCCC(O)/C=C/C(C)=O

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KISS1R Q969F8 1/20 0.43
ACHE P22303 1/20 0.39
BACE1 P56817 1/20 0.39
FAAH O00519 6/20 0.35
PPARG P37231 3/20 0.35
PPARD Q03181 1/20 0.35
PPARA Q07869 1/20 0.35
TRPA1 O75762 1/20 0.34
DDAH1 O94760 1/20 0.34
GAPDH P04406 1/20 0.34
MAPT P10636 1/20 0.34
CMKLR1 Q99788 1/20 0.33
OXER1 Q8TDS5 1/20 0.33
GPR132 Q9UNW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1782779 0.79 ACHE (0.59) ACHEBACE1PPARGTRPA1DDAH1
SCHEMBL1782776 0.79 ACHE (0.59) ACHEBACE1PPARGTRPA1DDAH1
SCHEMBL1783612 0.77 ACHE (0.41) ACHEBACE1PPARGTRPA1DDAH1
SCHEMBL1786850 0.77 TRPA1 (0.58) ACHEBACE1FAAHPPARGTRPA1
SCHEMBL1783611 0.77 ACHE (0.41) ACHEBACE1PPARGTRPA1DDAH1
SCHEMBL1786849 0.77 TRPA1 (0.58) ACHEBACE1FAAHPPARGTRPA1
SCHEMBL11572112 0.76 TRPA1 (0.56) ACHEBACE1PPARGTRPA1DDAH1
SCHEMBL11572115 0.76 TRPA1 (0.56) ACHEBACE1PPARGTRPA1DDAH1
SCHEMBL2048473 0.74
SCHEMBL1786712 0.74 ACHE (0.44) ACHEBACE1PPARGPPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192614-A1 METHOD FOR PREPARATION OF TRANS-N-BENZYLOXYCARBONYL-(3-HYDROXY-2-PIPERIDINYL)-2-PROPANONE AS INTERMEDIATE OF HALOFUGINONE CHENGDA PHARMACEUTICALS CO., LTD. (CN) 2023-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230192614-A1 METHOD FOR PREPARATION OF TRANS-N-BENZYLOXYCARBONYL-(3-HYDROXY-2-PIPERIDINYL)-2-PROPANONE AS INTERMEDIATE OF HALOFUGINONE TALDO1, RPL22, RPS20 KISS1R 4810/4885ACHE 3447/4885BACE1 2715/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.