SCHEMBL25759741

SCHEMBL25759741

O=S(=O)(NCCCCBr)c1ccc2ccccc2c1

nearest known ligand 0.66

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.66
NPY1R P25929 1/20 0.65
NPY5R Q15761 1/20 0.65
POLB P06746 1/20 0.57
LMNA P02545 1/20 0.57
GAA P10253 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
CYP19A1 P11511 1/20 0.56
HTR7 P34969 3/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30390387 1.00 ALDH1A1 (0.66) ALDH1A1NPY1RNPY5RPOLBLMNA
SCHEMBL10194532 0.95 ALDH1A1 (0.68) ALDH1A1NPY1RNPY5RPOLBLMNA
SCHEMBL30390015 0.89 ALDH1A1 (0.64) ALDH1A1NPY1RNPY5RPOLBLMNA
SCHEMBL25759592 0.89 ALDH1A1 (0.64) ALDH1A1NPY1RNPY5RPOLBLMNA
SCHEMBL3685227 0.85 ALDH1A1 (0.66) ALDH1A1NPY1RNPY5RPOLBLMNA
SCHEMBL1928807 0.85 CYP1A2 (0.67) ALDH1A1NPY1RNPY5RPOLBLMNA
SCHEMBL9927436 0.84 ALDH1A1 (0.68) ALDH1A1NPY1RNPY5RPOLB
Hydrochloric Acid SCHEMBL1846589 0.84 CYP1A2 (0.66) ALDH1A1NPY1RNPY5RPOLB
SCHEMBL9942078 0.84 NPY1R (0.67) ALDH1A1NPY1RNPY5RPOLBLMNA
SCHEMBL6791530 0.83 ALDH1A1 (0.68) ALDH1A1NPY1RNPY5RPOLBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230212121-A1 SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING MENTAL ILLNESS TRINEURO (KR) 2023-07-06 US disclosed
CN-116157124-A Sulfonamide derivative and pharmaceutical composition for preventing or treating mental diseases containing the same as active ingredient 大邱庆北尖端医疗产业振兴财团 2023-05-23 CN disclosed
WO-2021241875-A1 SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING MENTAL ILLNESS 재단법인 대구경북첨단의료산업진흥재단 2021-12-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230212121-A1 SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING MENTAL ILLNESS SLC6A2, SLC6A3, SLC6A4 ALDH1A1 1394/4885NPY1R 711/4885NPY5R 236/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.