SCHEMBL25759842

SCHEMBL25759842

CCN1CCC(c2c[nH]c3ccccc23)CC1

nearest known ligand 0.71

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ADRA1D P25100 4/20 0.67
SLC6A4 P31645 1/20 0.64
KDM4E B2RXH2 2/20 0.63
ATM Q13315 1/20 0.63
BRD4 O60885 1/20 0.63
ALDH1A1 P00352 1/20 0.63
POLB P06746 1/20 0.63
CREBBP Q92793 1/20 0.63
CYP2D6 P10635 1/20 0.62
KMT2A Q03164 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19210848 0.93 KDM4E (0.70) ADRA1DSLC6A4KDM4EATMBRD4
SCHEMBL14306777 0.88 ADRA1D (0.80) ADRA1DSLC6A4KDM4EATMCYP2D6
SCHEMBL4475225 0.85 ADRA1D (0.67) ADRA1DSLC6A4KDM4EATMBRD4
SCHEMBL27467624 0.85 ADRA1D (0.77) ADRA1DSLC6A4CYP2D6
SCHEMBL27482702 0.85 ADRA1D (0.63) ADRA1DSLC6A4KDM4EATMBRD4
SCHEMBL27897369 0.85 KDM4E (0.66) ADRA1DSLC6A4KDM4EATMBRD4
SCHEMBL14282282 0.84 ADRA1D (0.66) ADRA1DSLC6A4KDM4EATMBRD4
Hydrochloric Acid SCHEMBL7259157 0.84 ADRA1D (0.90) ADRA1DSLC6A4CYP2D6
SCHEMBL14280709 0.84 ADRA1D (0.80) ADRA1DSLC6A4CYP2D6
SCHEMBL30415306 0.83 KDM4E (0.83) ADRA1DKDM4EATMBRD4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230212121-A1 SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING MENTAL ILLNESS TRINEURO (KR) 2023-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230212121-A1 SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING MENTAL ILLNESS SLC6A2, SLC6A3, SLC6A4 ADRA1D 71/4885SLC6A4 3/4885KDM4E 2097/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.