Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.59 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYBB | P04839 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29501710 | 0.87 | SMN1; SMN2 (0.48) | IDO1CYP2D6CYP1A2PKMSMN1; SMN2 | |
| SCHEMBL3468892 | 0.85 | IDO1 (0.55) | IDO1AKR1B1HSPA5TAAR1CYP2D6 | |
| SCHEMBL1011357 | 0.83 | IDO1 (0.57) | IDO1AKR1B1HSPA5TAAR1CYP2D6 | |
| SCHEMBL1011358 | 0.82 | AKR1B1 (0.57) | IDO1AKR1B1HSPA5TAAR1CYP2D6 | |
| SCHEMBL5932257 | 0.82 | IDO1 (0.55) | IDO1AKR1B1HSPA5TAAR1CYP2D6 | |
| SCHEMBL9855769 | 0.81 | IDO1 (0.55) | IDO1AKR1B1HSPA5TAAR1CYP2D6 | |
| SCHEMBL28561113 | 0.81 | TYR (0.59) | IDO1AKR1B1HSPA5TAAR1CYP2D6 | |
| SCHEMBL446689 | 0.80 | SMN1; SMN2 (0.43) | CYP2D6CYP1A2PKMSMN1; SMN2NPSR1 | |
| SCHEMBL11064859 | 0.80 | IDO1 (0.53) | IDO1AKR1B1HSPA5TAAR1CYP2D6 | |
| SCHEMBL5933691 | 0.80 | IDO1 (0.53) | IDO1AKR1B1HSPA5TAAR1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103298602-A | Method for making silicone hydrogel contact lenses | NOVARTIS AG | 2013-09-11 | — | — | CN | claimed |
| CN-101641206-B | Prepolymers having polymer chains containing dangling polysiloxanes | NOVARTIS AG | 2013-03-20 | — | — | CN | claimed |
| CN-101065157-B | Biomedical devices containing amphiphilic block copolymers | JOHNSON & JOHNSON VISION CARE | 2012-01-04 | — | — | CN | claimed |
| CN-101641206-A | Prepolymers having polymer chains containing dangling polysiloxanes | NOVARTIS AG CH | 2010-02-03 | — | — | CN | claimed |
| CN-100578263-C | Wettable hydrogels comprising reactive, hydrophilic, polymeric internal wetting agents | JOHNSON & JOHNSON VISION CARE | 2010-01-06 | — | — | CN | claimed |
| CN-101065686-A | Wettable hydrogels containing reactive hydrophilic polymeric internal wetting agents | JOHNSON & JOHNSON VISION CARE (US) | 2007-10-31 | — | — | CN | claimed |
| CN-101065157-A | Biomedical devices containing amphiphilic block copolymers | JOHNSON & JOHNSON VISION CARE (US) | 2007-10-31 | — | — | CN | claimed |
| CN-112159401-B | Biased agonist and medical application thereof | 中国人民解放军军事科学院军事医学研究院 | 2022-06-03 | — | — | CN | disclosed |
| CN-112159401-A | Biased agonist and medical application thereof | 中国人民解放军军事科学院军事医学研究院 | 2021-01-01 | — | — | CN | disclosed |
| CN-103998230-A | Gas barrier film | KONICA MINOLTA INC | 2014-08-20 | — | — | CN | disclosed |
| EP-2751076-A1 | SYNTHESIS METHOD AND INTERMEDIATES USEFUL IN THE PREPARATION OF PYRROLOBENZODIAZEPINES | Spirogen Sàrl (CH) | 2014-07-09 | — | — | EP | disclosed |
| CN-103777254-A | Method for manufacturing soft siloxane hydrogel contact lens | NOVARTIS AG | 2014-05-07 | — | — | CN | disclosed |
| CN-102239431-B | Ophthalmic device for providing hydrophobic comfort agents | NOVARTIS AG | 2014-03-19 | — | — | CN | disclosed |
| CN-101065686-A | Wettable hydrogels containing reactive hydrophilic polymeric internal wetting agents | JOHNSON & JOHNSON VISION CARE (US) | 2007-10-31 | — | — | CN | disclosed |
| CN-101005822-A | Oily cosmetic preparation | SHISEIDO CO LTD (JP) | 2007-07-25 | — | — | CN | disclosed |
| CN-1976692-A | Methods and compositions for treating ophthalmic conditions with retinyl derivates | SIRION THERAPEUTICS INC (US) | 2007-06-06 | — | — | CN | disclosed |
| CN-1902250-A | Dibenzosilol polymers, their preparation and uses | CAMBRIDGE DISPLAY TECH LTD (GB) | 2007-01-24 | — | — | CN | disclosed |
| CN-1289157-C | Biomedical devices containing internal wetting agents | JOHNSON & JOHNSON VISION CARE (US) | 2006-12-13 | — | — | CN | disclosed |
| CN-1635915-A | Biomedical devices containing internal wetting agents | JOHNSON & JOHNSON VISION CARE (US) | 2005-07-06 | — | — | CN | disclosed |
| US-5561119-A | ANTITUMOR AGENTS | LABORATOIRES HOECHST (FR) | 1996-10-01 | — | — | US | disclosed |