SCHEMBL446689

SCHEMBL446689

NC(=O)OCc1ccccc1N

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.43
CYP1A2 P05177 2/20 0.43
CYP2D6 P10635 1/20 0.43
PKM P14618 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
ALDH1A1 P00352 9/20 0.42
HSD17B10 Q99714 6/20 0.42
LMNA P02545 2/20 0.42
FDPS P14324 1/20 0.41
TSHR P16473 2/20 0.39
HPGD P15428 4/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
TP53 P04637 1/20 0.38
GLA P06280 1/20 0.38
CYP3A4 P08684 1/20 0.38
MAPK1 P28482 1/20 0.38
HIF1A Q16665 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29501710 0.87 SMN1; SMN2 (0.48) SMN1; SMN2CYP1A2CYP2D6PKMNPSR1
SCHEMBL1560611 0.86 ALDH1A1 (0.43) SMN1; SMN2ALDH1A1HSD17B10FDPSTSHR
SCHEMBL31253930 0.84 ALDH1A1 (0.42) SMN1; SMN2ALDH1A1HSD17B10FDPSTSHR
SCHEMBL31253931 0.84 ALDH1A1 (0.42) SMN1; SMN2ALDH1A1HSD17B10FDPSTSHR
SCHEMBL11462044 0.84 ALDH1A1 (0.42) SMN1; SMN2ALDH1A1HSD17B10FDPSTSHR
SCHEMBL10557874 0.82 ALDH1A1 (0.55) SMN1; SMN2CYP1A2ALDH1A1HSD17B10LMNA
SCHEMBL13873296 0.81 LMNA (0.51) SMN1; SMN2CYP1A2CYP2D6PKMNPSR1
SCHEMBL18813518 0.81 ALDH1A1 (0.40) SMN1; SMN2ALDH1A1HSD17B10FDPSTSHR
SCHEMBL4618502 0.80 SMN1; SMN2 (0.51) SMN1; SMN2CYP1A2CYP2D6PKMNPSR1
SCHEMBL1043545 0.80 CYP4F2 (0.46) SMN1; SMN2CYP1A2CYP2D6PKMNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 295 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260125418-A1 A COMPOUND AND ITS USE FOR DETECTING A DISEASE IN THE EXHALED BREATH OF A SUBJECT OWLSTONE MED LTD (GB) 2026-05-07 US claimed
EP-4598592-A1 A COMPOUND AND ITS USE FOR DETECTING A DISEASE IN THE EXHALED BREATH OF A SUBJECT Owlstone Medical Limited (GB) 2025-08-13 EP claimed
CN-120152745-A Compounds and their use for detecting diseases in exhaled breath of a subject 奥斯通医疗有限公司 2025-06-13 CN claimed
WO-2024074813-A1 A COMPOUND AND ITS USE FOR DETECTING A DISEASE IN THE EXHALED BREATH OF A SUBJECT OWLSTONE MEDICAL LIMITED (GB) 2024-04-11 WO claimed
WO-2024044549-A1 VHH ANTIBODY CONJUGATES Abdera Therapeutics Inc. (US) 2024-02-29 WO claimed
WO-2024044552-A1 VHH ANTIBODY DOTA CONJUGATES Abdera Therapeutics Inc. (US) 2024-02-29 WO claimed
WO-2024044554-A1 VHH ANTIBODY CONJUGATES WITH HETEROARYL CHELATORS Abdera Therapeutics Inc. (US) 2024-02-29 WO claimed
CN-116457023-A antibody-TLR agonist conjugates, methods and uses thereof AMBRX公司 2023-07-18 CN claimed
WO-2021184020-A1 METHODS OF TREATING NEUROINFLAMMATION CODIAK BIOSCIENCES, INC. (US) 2021-09-16 WO claimed
WO-2014089146-A1 COMPOSITIONS AND METHODS FOR IN VIVO DELIVERY OF ANTISENSE COMPOUNDS ISIS PHARMACEUTICALS, INC. (US) 2014-06-12 WO claimed
EP-2651420-A2 PEPTIDE-BASED IN VIVO SIRNA DELIVERY SYSTEM Arrowhead Research Corporation (US) 2013-10-23 EP claimed
US-8501930-B2 Peptide-based in vivo siRNA delivery system Arrowhead Madison Inc. (US) 2013-08-06 US claimed
US-20120165393-A1 Peptide-Based In Vivo siRNA Delivery System Arrowhead Madison Inc. (US) 2012-06-28 US claimed
WO-2012083185-A2 PEPTIDE-BASED IN VIVO SIRNA DELIVERY SYSTEM ARROWHEAD RESEARCH CORPORATIONS (US) 2012-06-21 WO claimed
US-20260125418-A1 A COMPOUND AND ITS USE FOR DETECTING A DISEASE IN THE EXHALED BREATH OF A SUBJECT OWLSTONE MED LTD (GB) 2026-05-07 US disclosed
US-20260027147-A1 EXTRACELLULAR VESICLE-ASO CONSTRUCTS TARGETING CEBP/BETA LONZA SALES AG (CH) 2026-01-29 US disclosed
EP-4598592-A1 A COMPOUND AND ITS USE FOR DETECTING A DISEASE IN THE EXHALED BREATH OF A SUBJECT Owlstone Medical Limited (GB) 2025-08-13 EP disclosed
CN-1321715-A Adhesive of fixing matrix for microelectronic device NAT STARCH & CHEMICAL INVEST H (US) 2001-11-14 CN disclosed
CN-1253969-A Circuit element prepared with allylated amide compound NAT STARCH CHEM INVEST (US) 2000-05-24 CN disclosed
EP-0317956-A2 Anti-tumor prodrugs Bristol-Myers Squibb Company (US) 1989-05-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120165393-A1 Peptide-Based In Vivo siRNA Delivery System VIP, RNASE1, APLNR SMN1; SMN2 2653/4885CYP1A2 4864/4885CYP2D6 4663/4885
US-20260125418-A1 A COMPOUND AND ITS USE FOR DETECTING A DISEASE IN THE EXHALED BREATH OF A SUBJECT BRCA1, L3MBTL1, LMNA SMN1; SMN2 186/4885CYP1A2 2022/4885CYP2D6 1797/4885
US-20260027147-A1 EXTRACELLULAR VESICLE-ASO CONSTRUCTS TARGETING CEBP/BETA CEBPZ, OSBP, DIS3 SMN1; SMN2 1119/4885CYP1A2 4876/4885CYP2D6 4482/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.