Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | CYBB | P04839 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2295732 | 0.85 | IDO1 (0.53) | IDO1TAAR1AKR1B1HSPA5TYR | |
| SCHEMBL11064859 | 0.85 | IDO1 (0.53) | IDO1TAAR1AKR1B1HSPA5TYR | |
| SCHEMBL10956714 | 0.83 | IDO1 (0.52) | IDO1TAAR1AKR1B1HSPA5TYR | |
| SCHEMBL18813518 | 0.81 | ALDH1A1 (0.40) | TSHRHIF1AALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL27345802 | 0.81 | IDO1 (0.50) | IDO1AKR1B1HSPA5TYRKEAP1 | |
| SCHEMBL2575989 | 0.81 | IDO1 (0.59) | IDO1TAAR1AKR1B1HSPA5TYR | |
| SCHEMBL1011357 | 0.80 | IDO1 (0.57) | IDO1TAAR1AKR1B1HSPA5TYR | |
| SCHEMBL5971822 | 0.80 | PPARG (0.38) | ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL28430932 | 0.80 | POLB (0.54) | IDO1TAAR1ALDH1A1L3MBTL1 | |
| SCHEMBL27788422 | 0.80 | AKR1B1 (0.55) | IDO1AKR1B1HSPA5TYRKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409199-A2 | Rigid polyurethanepolyisocyanurate foams and process for preparing the same | THE DOW CHEMICAL COMPANY (US) | 1991-01-23 | — | — | EP | disclosed |
| EP-0400443-A2 | Polyurethane foams manufactured with mixed gas/liquid blowing agents | THE DOW CHEMICAL COMPANY (a Delaware corporation) (US) | 1990-12-05 | — | — | EP | disclosed |