Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | TACR1 | P25103 | 1/20 | 0.50 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9707213 | 0.86 | TSHR (0.58) | TACR1HSP90AB1CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL31012122 | 0.84 | CYP1A2 (0.56) | HSP90AB1CYP1A2CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL4850585 | 0.84 | CYP1A2 (0.56) | HSP90AB1CYP1A2CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL31065555 | 0.83 | IDO1 (0.46) | TACR1HSP90AB1CYP1A2CYP2C19LMNA | |
| SCHEMBL10269557 | 0.80 | FFAR1 (0.43) | HSP90AB1L3MBTL1AKR1B1FFAR1 | |
| SCHEMBL29417924 | 0.79 | CYP2C19 (0.53) | CYP1A2CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL7629984 | 0.79 | CYP2C19 (0.53) | CYP1A2CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL12270341 | 0.79 | KCNH2 (0.51) | KCNH2TACR1TSHRDHODH | |
| Hydroxyamine SCHEMBL8924246 | 0.78 | MEN1 (0.53) | HSP90AB1CYP1A2CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL15249121 | 0.78 | PARP10 (0.61) | KCNH2LMNAAKR1B1FFAR1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2399585-A1 | Boronic acids and esters as inhibitors of fatty acid amide hydrolase | Infinity Pharmaceuticals, Inc. (US) | 2011-12-28 | — | — | EP | disclosed |
| EP-2073816-B1 | BORONIC ACIDS AND ESTERS AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE | INFINITY PHARMACEUTICALS INC (US) | 2011-09-14 | — | — | EP | disclosed |