SCHEMBL2576

SCHEMBL2576

[c]1ccc(-c2ccccc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.60
MAPK1 P28482 2/20 0.43
TAAR1 Q96RJ0 2/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
HSD17B10 Q99714 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
NOTUM Q6P988 1/20 0.43
MMP3 P08254 1/20 0.43
BCL2L1 Q07817 1/20 0.43
ATM Q13315 1/20 0.39
SLC22A2 O15244 1/20 0.39
SLC22A1 O15245 1/20 0.39
SLC22A3 O75751 1/20 0.39
SLC6A4 P31645 1/20 0.39
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
MAOA P21397 1/20 0.38
NFKB1 P19838 1/20 0.38
NFKB2 Q00653 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27488237 0.97 ALDH1A1 (0.56) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
SCHEMBL9334552 0.97 ALDH1A1 (0.56) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
SCHEMBL28993681 0.97 ALDH1A1 (0.56) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
SCHEMBL27686618 0.97 ALDH1A1 (0.56) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
SCHEMBL2448872 0.97 ALDH1A1 (0.56) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
SCHEMBL3886287 0.97 ALDH1A1 (0.56) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
SCHEMBL27623254 0.97 ALDH1A1 (0.56) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
Hydrochloric Acid SCHEMBL28609394 0.97 ALDH1A1 (0.56) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
SCHEMBL25683 0.97 ALDH1A1 (0.56) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
SCHEMBL27623253 0.97 ALDH1A1 (0.56) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 18785 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118344695-A Hydroxyl-enriched cycloolefin copolymer long afterglow material and application thereof 重庆理工大学 2024-07-16 CN claimed
US-12041848-B2 Heterocyclic compound and organic light emitting element comprising same LG CHEM, LTD. (KR) 2024-07-16 US claimed
CN-118324804-A Aromatic phosphonate compound and synthesis method thereof 海南大学 2024-07-12 CN claimed
CN-118290379-A Preparation method of novel agricultural multifunctional substance and application of novel agricultural multifunctional substance in aspects of resisting virus, inhibiting bacteria and promoting plant growth 贵州工业职业技术学院 2024-07-05 CN claimed
US-20240219829-A1 HYDROPHOBIC CROSSLINKABLE PINNING UNDERLAYERS WITH IMPROVED DRY ETCH CAPABILITIES FOR PATTERNING DIRECTED SELF-ASSEMBLY OF PS-B-PMMA TYPE BLOCK COPOLYMERS MERCK PATENT GMBH (DE) 2024-07-04 US claimed
US-20240207253-A1 Inhibitors of CDR1 for Reversal of Azole Drug Resistance in Fungal Infections THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS 2024-06-27 US claimed
EP-4387978-A1 7-SUBSTITUTED 7-DEAZAADENINE-CONTAINING 2',3'-CYCLIC DINUCLEOTIDES Ustav Organicke Chemie a Biochemie AV CR, v.v.i. (CZ) 2024-06-26 EP claimed
CN-118241229-A Stereoselective synthesis method of 1, 4-dicarbonyl-Z olefin 青岛科技大学 2024-06-25 CN claimed
CN-118221624-A Benzofuran spiro bicyclo [2.1.1] hexane derivative and synthesis method thereof 浙江师范大学 2024-06-21 CN claimed
US-20240197888-A1 SOS1 PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS BIOTHERYX, INC. 2024-06-20 US claimed
US-4005098-A BRIGHTENING AGENTS BAYER AKTIENGESELLSCHAFT (DT) 1977-01-25 US claimed
US-4001130-A DETERGENTS, SUBSTITUTED BUTADIENES HOECHST AKTIENGESELLSCHAFT (DT) 1977-01-04 US claimed
US-3998803-A TEXTILES FIDELITY UNION TRUST COMPANY, EXECUTIVE TRUSTEE UNDER THE SANDOZ TRUST (US) 1976-12-21 US claimed
US-3993645-A Stilbene optical brighteners and compositions brightened therewith STERLING DRUG INC. (US) 1976-11-23 US claimed
US-3991049-A Aromatic compounds containing ethylene double bonds, processes for their manufacture and use CIBA-GEIGY AG (CH) 1976-11-09 US claimed
US-3984399-A OPTICAL BRIGHTENERS CIBA-GEIGY AG (CH) 1976-10-05 US claimed
US-3979440-A PROSTAGLANDINS THE UPJOHN COMPANY (US) 1976-09-07 US claimed
US-3959292-A HYPOTENSIVE AGENTS, CORONARY DILATORS BAYER AKTIENGESELLSCHAFT (DT) 1976-05-25 US claimed
US-3956427-A STABILIZERS CIBA-GEIGY CORPORATION (US) 1976-05-11 US claimed
US-3932301-A NYLON, POLYESTERS STERLING DRUG INC. (US) 1976-01-13 US claimed