SCHEMBL3886287

SCHEMBL3886287

[NaH].[c]1ccc(-c2ccccc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.56
MAPK1 P28482 2/20 0.41
TAAR1 Q96RJ0 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
HSD17B10 Q99714 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
NOTUM Q6P988 1/20 0.41
MMP3 P08254 1/20 0.41
BCL2L1 Q07817 1/20 0.41
ATM Q13315 1/20 0.38
SLC22A2 O15244 1/20 0.38
SLC22A1 O15245 1/20 0.38
SLC22A3 O75751 1/20 0.38
SLC6A4 P31645 1/20 0.38
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
MAOA P21397 1/20 0.36
NFKB1 P19838 1/20 0.36
NFKB2 Q00653 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2576 0.97 ALDH1A1 (0.60) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
SCHEMBL9334552 0.94 ALDH1A1 (0.56) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
Hydrochloric Acid SCHEMBL28609394 0.94 ALDH1A1 (0.56) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
SCHEMBL27623254 0.94 ALDH1A1 (0.56) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
SCHEMBL27488237 0.94 ALDH1A1 (0.56) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
SCHEMBL2448872 0.94 ALDH1A1 (0.56) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
SCHEMBL27531830 0.94 ALDH1A1 (0.56) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
SCHEMBL28993681 0.94 ALDH1A1 (0.56) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
SCHEMBL25683 0.94 ALDH1A1 (0.56) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
SCHEMBL27686621 0.94 ALDH1A1 (0.56) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7572303-B2 A symmetrical dialkyl carbonate, a metal, borong, silicon, or group 7 compound, a hydrogen or hydrocarbon-based fuel, an oxidizer, and a metallic cocatalyst; minimized hydrolysis; improved combustion and storage stability OCTANE INTERNATIONAL, LTD. (US) 2009-08-11 US disclosed
EP-0954558-B1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR WILLIAM C (US) 2006-06-14 EP disclosed
US-20050044778-A1 Fuel compositions employing catalyst combustion structure OCTANE INTERNATIONAL, LTD. 2005-03-03 US disclosed
US-20040237384-A1 Fuel compositions exhibiting improved fuel stability OCTANE INTERNATIONAL, LTD. 2004-12-02 US disclosed
US-6652608-B1 Fuel compositions exhibiting improved fuel stability OCTANE INTERNATIONAL, LTD. 2003-11-25 US disclosed
EP-1051461-A2 FUEL COMPOSITIONS EMPLOYING CATALYST COMBUSTION STRUCTURE ORR, William C. (US) 2000-11-15 EP disclosed
WO-1999066009-A2 FUEL COMPOSITIONS EMPLOYING CATALYST COMBUSTION STRUCTURE ORR WILLIAM C (US) 1999-12-23 WO disclosed
EP-0954558-A1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR, William C. (US) 1999-11-10 EP disclosed
WO-1998026028-A1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR WILLIAM C (US) 1998-06-18 WO disclosed