Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.35 |
| ▸ | FURIN | P09958 | 7/20 | 0.35 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.33 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | FAP | Q12884 | 1/20 | 0.33 |
| ▸ | NPY4R | P50391 | 5/20 | 0.32 |
| ▸ | NPY1R | P25929 | 3/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | NMT2 | O60551 | 1/20 | 0.31 |
| ▸ | NMT1 | P30419 | 1/20 | 0.31 |
| ▸ | NPY2R | P49146 | 2/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.31 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25760203 | 0.85 | FURIN (0.41) | FURINC3AR1SIRT6SIRT1PRSS1 | |
| SCHEMBL29590144 | 0.85 | GLO1 (0.39) | DPP4DPP8DPP9DPP7FURIN | |
| SCHEMBL22927849 | 0.83 | DPP4 (0.36) | DPP4DPP8DPP9DPP7FURIN | |
| SCHEMBL29233240 | 0.81 | DPP4 (0.39) | DPP4DPP8DPP9DPP7FURIN | |
| SCHEMBL23394645 | 0.81 | DPP7 (0.40) | DPP4DPP8DPP9DPP7C3AR1 | |
| SCHEMBL21323139 | 0.81 | DPP4 (0.40) | DPP4DPP8DPP9DPP7C3AR1 | |
| SCHEMBL21233231 | 0.81 | DPP4 (0.40) | DPP4DPP8DPP9DPP7C3AR1 | |
| SCHEMBL20385917 | 0.81 | DPP7 (0.40) | DPP4DPP8DPP9DPP7C3AR1 | |
| SCHEMBL19450715 | 0.81 | DPP7 (0.40) | DPP4DPP8DPP9DPP7C3AR1 | |
| SCHEMBL25761146 | 0.81 | DPP7 (0.45) | DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3328827-B1 | PRODRUGS OF GLUTAMINE ANALOGS | UNIV JOHNS HOPKINS (US) | 2023-07-05 | — | — | EP | disclosed |