Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | MITF | O75030 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.42 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8737442 | 0.92 | SLC6A4 (0.49) | HTTL3MBTL1ALDH1A1GAACARM1 | |
| SCHEMBL10597815 | 0.88 | KCNA3 (0.51) | HTTL3MBTL1TDP1ALDH1A1GAA | |
| SCHEMBL7457094 | 0.86 | KCNA3 (0.52) | HTTL3MBTL1TDP1ALDH1A1GAA | |
| SCHEMBL2354199 | 0.85 | ALDH1A1 (0.62) | HTTL3MBTL1TDP1ALDH1A1GAA | |
| SCHEMBL2078871 | 0.82 | L3MBTL1 (0.54) | HTTL3MBTL1TDP1ALDH1A1GAA | |
| SCHEMBL441860 | 0.80 | KCNA3 (0.58) | HTTL3MBTL1TDP1ALDH1A1GAA | |
| SCHEMBL29860318 | 0.80 | KCNA3 (0.58) | HTTL3MBTL1TDP1ALDH1A1GAA | |
| SCHEMBL15085780 | 0.80 | SMN1; SMN2 (0.60) | HTTL3MBTL1TDP1ALDH1A1GAA | |
| SCHEMBL83816 | 0.80 | TDP1 (0.61) | HTTL3MBTL1TDP1ALDH1A1GAA | |
| SCHEMBL12260794 | 0.80 | CA1 (0.57) | HTTL3MBTL1ALDH1A1GAACARM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2404607-A1 | Boronic acids and esters as inhibitors of fatty acid amide hydrolase | Infinity Pharmaceuticals, Inc. (US) | 2012-01-11 | — | — | EP | disclosed |
| EP-2399585-A1 | Boronic acids and esters as inhibitors of fatty acid amide hydrolase | Infinity Pharmaceuticals, Inc. (US) | 2011-12-28 | — | — | EP | disclosed |