SCHEMBL2576177

SCHEMBL2576177

CCC(C)NC(=O)OC1CC(C)CC(C)(C)C1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.47
▸ LMNA P02545 2/20 0.47
▸ CYP3A4 P08684 1/20 0.47
▸ CYP1A2 P05177 1/20 0.47
▸ CYP2C9 P11712 1/20 0.47
▸ CYP2C19 P33261 1/20 0.47
▸ NR1I2 O75469 1/20 0.45
▸ ABCB11 O95342 1/20 0.45
▸ MEN1 O00255 2/20 0.38
▸ KMT2A Q03164 2/20 0.38
▸ BCHE P06276 1/20 0.36
▸ CTDSP1 Q9GZU7 1/20 0.36
▸ CTSV O60911 2/20 0.34
▸ CTSL P07711 2/20 0.34
▸ CTSS P25774 2/20 0.34
▸ CTSK P43235 2/20 0.34
▸ CCNE1 P24864 7/20 0.34
▸ CDK2 P24941 7/20 0.34
▸ GSK3B P49841 5/20 0.34
▸ EPHX1 P07099 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2580697 0.80 EPHX1 (0.50) ALDH1A1LMNACYP3A4CYP1A2CYP2C9
SCHEMBL17639951 0.78 LMNA (0.54) ALDH1A1LMNACYP3A4CYP1A2CYP2C9
SCHEMBL13091245 0.77 ALDH1A1 (0.51) ALDH1A1LMNACYP3A4CYP1A2CYP2C9
SCHEMBL11591288 0.77 ALDH1A1 (0.56) ALDH1A1LMNACYP3A4CYP1A2CYP2C9
SCHEMBL11591282 0.77 ALDH1A1 (0.56) ALDH1A1LMNACYP3A4CYP1A2CYP2C9
SCHEMBL4630600 0.76 LMNA (0.54) ALDH1A1LMNACYP3A4CYP1A2CYP2C9
SCHEMBL4629992 0.76 LMNA (0.54) ALDH1A1LMNACYP3A4CYP1A2CYP2C9
SCHEMBL4629991 0.76 LMNA (0.54) ALDH1A1LMNACYP3A4CYP1A2CYP2C9
SCHEMBL11591693 0.76 LMNA (0.54) ALDH1A1LMNACYP3A4CYP1A2CYP2C9
SCHEMBL4629990 0.76 LMNA (0.54) ALDH1A1LMNACYP3A4CYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2593078-B1 CYCLOHEXYL CARBAMATE COMPOUNDS AS ACTIVE ANTI-CELLULITE INGREDIENTS SYMRISE AG (DE) 2016-11-30 — — EP disclosed
EP-2593078-B1 CYCLOHEXYL CARBAMATE COMPOUNDS AS ACTIVE ANTI-CELLULITE INGREDIENTS SYMRISE AG (DE) 2016-11-30 — — EP disclosed
EP-2593077-B1 CYCLOHEXYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES SYMRISE AG (DE) 2016-11-02 — — EP disclosed
EP-2593077-B1 CYCLOHEXYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES SYMRISE AG (DE) 2016-11-02 — — EP disclosed
CN-103002868-B As the carbamic acid cyclohexyl compound of active fat melting composition SYMRISE AG (DE) 2016-05-04 — — CN disclosed
CN-103025310-B Cyclohexyl carbamate compounds as skin and/or hair lightening actives SYMRISE AG (DE) 2016-01-27 — — CN disclosed
US-9072676-B2 Cyclohexyl carbamate compounds as skin and/or hair lightening actives SYMRISE AG (DE) 2015-07-07 — — US disclosed
US-9072676-B2 Cyclohexyl carbamate compounds as skin and/or hair lightening actives SYMRISE AG (DE) 2015-07-07 — — US disclosed
US-9072676-B2 Cyclohexyl carbamate compounds as skin and/or hair lightening actives SYMRISE AG (DE) 2015-07-07 — — US disclosed
US-9012497-B2 Cyclohexyl carbamate compounds as active anti-cellulite ingredients SYMRISE AG (DE) 2015-04-21 — — US disclosed
EP-2593078-A2 CYCLOHEXYL CARBAMATE COMPOUNDS AS ACTIVE ANTI-CELLULITE INGREDIENTS Symrise AG (DE) 2013-05-22 — — EP disclosed
EP-2593077-A2 CYCLOHEXYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES Symrise AG (DE) 2013-05-22 — — EP disclosed
CN-103025310-A Cyclohexyl carbamate compounds as skin and/or hair lightening actives SYMRISE GMBH & CO KG 2013-04-03 — — CN disclosed
CN-103002868-A Cyclohexyl carbamate compounds as active anti-cellulite ingredients SYMRISE GMBH & CO KG 2013-03-27 — — CN disclosed
EP-2389922-A1 Cyclohexyl carbamate compounds as anti-ageing actives Symrise AG (DE) 2011-11-30 — — EP disclosed
EP-2389922-A1 Cyclohexyl carbamate compounds as anti-ageing actives Symrise AG (DE) 2011-11-30 — — EP disclosed
WO-2010122178-A2 CYCLOHEXYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES SYMRISE GMBH & CO. KG (DE) 2010-10-28 — — WO disclosed
WO-2010122178-A2 CYCLOHEXYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES SYMRISE GMBH & CO. KG (DE) 2010-10-28 — — WO disclosed
WO-2010097479-A2 CYCLOHEXYL CARBAMATE COMPOUNDS AS ACTIVE ANTI-CELLULITE INGREDIENTS SYMRISE GMBH & CO. KG (DE) 2010-09-02 — — WO disclosed
WO-2010097479-A2 CYCLOHEXYL CARBAMATE COMPOUNDS AS ACTIVE ANTI-CELLULITE INGREDIENTS SYMRISE GMBH & CO. KG (DE) 2010-09-02 — — WO disclosed
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