Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18616102 | 0.79 | TRPA1 (0.32) | TRPA1TRPM8 | |
| SCHEMBL25762180 | 0.76 | TRPA1 (0.32) | TRPA1TRPM8 | |
| SCHEMBL25762183 | 0.76 | TRPA1 (0.36) | TRPA1TRPM8 | |
| SCHEMBL23612748 | 0.74 | — | — | |
| SCHEMBL25832188 | 0.72 | TRPA1 (0.36) | TRPA1TRPM8 | |
| SCHEMBL14116089 | 0.69 | TRPA1 (0.61) | TRPA1TRPM8 | |
| SCHEMBL12418413 | 0.69 | — | — | |
| SCHEMBL20034835 | 0.69 | — | — | |
| SCHEMBL20009102 | 0.67 | — | — | |
| SCHEMBL9498905 | 0.67 | TRPA1 (0.35) | TRPA1TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203063-A1 | TRICYCLIC PYRIDONES AND PYRIMIDONES | ERASCA, INC. | 2023-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230203063-A1 | TRICYCLIC PYRIDONES AND PYRIMIDONES | TYMS, TYMP, DHFR | TRPA1 3963/4885TRPM8 4182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.