Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLRMT | O00411 | 1/20 | 0.44 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.32 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | AKT2 | P31751 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.32 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.32 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.32 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.32 |
| ▸ | ADK | P55263 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25077182 | 0.90 | POLRMT (0.43) | POLRMTDOT1LGPR34P2RY10GPR174 | |
| SCHEMBL25077245 | 0.89 | POLRMT (0.45) | POLRMTDOT1LPIK3R1AKT1AKT2 | |
| SCHEMBL25764487 | 0.89 | POLRMT (0.45) | POLRMTDOT1LPIK3R1AKT1AKT2 | |
| SCHEMBL25769362 | 0.89 | POLRMT (0.41) | POLRMTDOT1LPIK3R1AKT1AKT2 | |
| SCHEMBL26286057 | 0.88 | POLRMT (0.48) | POLRMTPIK3R1AKT1AKT2PIK3CA | |
| SCHEMBL25077236 | 0.86 | POLRMT (0.45) | POLRMTDOT1LADK | |
| SCHEMBL25077210 | 0.86 | POLRMT (0.51) | POLRMTDOT1LADK | |
| SCHEMBL26285621 | 0.86 | POLRMT (0.51) | POLRMTDOT1LADK | |
| SCHEMBL25077302 | 0.85 | POLRMT (0.46) | POLRMTDOT1LADK | |
| SCHEMBL25772840 | 0.84 | POLRMT (0.35) | POLRMTGPR34P2RY10GPR174 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230212199-A1 | PHOSPHOLIPID COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | GILEAD SCIENCES, INC. | 2023-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230212199-A1 | PHOSPHOLIPID COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | PHOSPHO1, SGMS1, SGMS2 | POLRMT 266/4885DOT1L 2986/4885PIK3R1 1117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.