Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2724950 | 0.92 | ATM (0.36) | ATMALDH1A1TSHRPARP1MEN1 | |
| SCHEMBL8132766 | 0.85 | ELANE (0.36) | ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL21818930 | 0.83 | ATM (0.42) | ATMALDH1A1HSD17B10PARP1SMN1; SMN2 | |
| SCHEMBL21834515 | 0.83 | ATM (0.42) | ATMALDH1A1HSD17B10PARP1SMN1; SMN2 | |
| SCHEMBL30872413 | 0.83 | MEN1 (0.39) | ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL30911168 | 0.83 | MEN1 (0.39) | ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL6677041 | 0.79 | MEN1 (0.35) | ALDH1A1MEN1KMT2A | |
| SCHEMBL25230409 | 0.76 | ALDH1A1 (0.42) | ATMALDH1A1TSHRHSD17B10PARP1 | |
| SCHEMBL973127 | 0.76 | KLK7 (0.49) | PARP1UCHL1 | |
| SCHEMBL4766170 | 0.76 | HSD17B10 (0.42) | ATMALDH1A1HSD17B10NPC1UCHL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023113534-A1 | METHOD FOR PREPARATION OF (2R, 3S)-2-(BENZO[D]IMIDAZOLYLPROPYL)PIPERIDIN-3-OL DERIVATIVES | 주식회사 대웅제약 | 2023-06-22 | — | — | WO | disclosed |
| CN-113480471-A | Multi-chiral nitrogen-substituted piperidinol derivative and preparation method thereof | 长兴宜生药物科技有限公司 | 2021-10-08 | — | — | CN | disclosed |