Thebacon

Thebacon

SCHEMBL25766

COc1ccc2c3c1O[C@H]1C(OC(C)=O)=CC[C@H]4[C@@H](C2)N(C)CC[C@]314

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
OPRD1 P41143 12/20 0.63
OPRM1 P35372 12/20 0.63
OPRK1 P41145 8/20 0.63
MRGPRX2 Q96LB1 4/20 0.63
PDE4D Q08499 2/20 0.63
LMNA P02545 1/20 0.63
ADRB1 P08588 1/20 0.52
PDE3A Q14432 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thebacon SCHEMBL21304123 1.00 OPRD1 (0.63) OPRD1OPRM1OPRK1MRGPRX2PDE4D
Thebacon SCHEMBL1649199 1.00 OPRD1 (0.63) OPRD1OPRM1OPRK1MRGPRX2PDE4D
Thebacon SCHEMBL29632752 1.00 OPRD1 (0.63) OPRD1OPRM1OPRK1MRGPRX2PDE4D
Thebacon SCHEMBL6240045 0.99 OPRD1 (0.62) OPRD1OPRM1OPRK1MRGPRX2PDE4D
SCHEMBL16922127 0.95 OPRD1 (0.59) OPRD1OPRM1OPRK1MRGPRX2PDE4D
SCHEMBL18457704 0.90 OPRM1 (0.51) OPRD1OPRM1OPRK1MRGPRX2PDE4D
SCHEMBL12944986 0.90 OPRM1 (0.51) OPRD1OPRM1OPRK1MRGPRX2PDE4D
SCHEMBL10222572 0.90 OPRM1 (0.51) OPRD1OPRM1OPRK1MRGPRX2PDE4D
SCHEMBL18457702 0.90 OPRM1 (0.51) OPRD1OPRM1OPRK1MRGPRX2PDE4D
SCHEMBL12006856 0.90 OPRM1 (0.68) OPRD1OPRM1OPRK1MRGPRX2PDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2209 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240288374-A1 PLASMONIC NANOPARTICLE PLATFORM FOR ANALYTE DETECTION Zymeron Corporation 2024-08-29 US claimed
WO-2024172892-A1 PLASMONIC NANOPARTICLE PLATFORM FOR ANALYTE DETECTION Zymeron Corporation (US) 2024-08-22 WO claimed
US-20240165022-A1 Pharmaceutical Formulation KLARIA PHARMA HOLDING AB (SE) 2024-05-23 US claimed
US-11904049-B2 Pharmaceutical formulation KLARIA PHARMA HOLDING AB (SE) 2024-02-20 US claimed
US-11771695-B2 Cannabinoid receptor modulators ARENA PHARMACEUTICALS, INC. (US) 2023-10-03 US claimed
EP-3385252-B1 CANNABINOID RECEPTOR MODULATORS ARENA PHARM INC (US) 2022-09-21 EP claimed
US-20220241274-A1 CANNABINOID RECEPTOR MODULATORS ARENA PHARMACEUTICALS, INC. 2022-08-04 US claimed
WO-2022159506-A1 DEUTERATED CANNABIDIOL COMPOUNDS MERIT THERAPEUTICS, INC. (US) 2022-07-28 WO claimed
WO-2022159507-A1 COMBINATION OF CANNABINOIDS WITH ADDITIONAL THERAPEUTIC AGENTS FOR TREATING DISEASES OR DISORDERS MERIT THERAPEUTICS, INC. (US) 2022-07-28 WO claimed
EP-1931320-B1 MICROPARTICLES WITH MODIFIED RELEASE OF AT LEAST ONE ACTIVE PRINCIPLE AND ORAL DOSAGE FORM COMPRISING THE SAME FLAMEL IRELAND LTD (IE) 2022-06-15 EP claimed
EP-1121109-A2 OPIOID ANALGESIC Euroceltique S.A. (LU) 2001-08-08 EP claimed
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 EP claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 WO claimed
WO-2000021520-A2 OPIOID ANALGESIC EUROCELTIQUE S.A. (LU) 2000-04-20 WO claimed
EP-0984974-A1 GLYCOCONJUGATES OF OPIATED SUBSTANCES ROLABO S.L. (ES) 2000-03-15 EP claimed
WO-1998054196-A1 GLYCOCONJUGATES OF OPIATED SUBSTANCES ROLABO SL (ES) 1998-12-03 WO claimed
CN-1196955-A Thebaica giving-up vaccinum for man KUNMING BIOLOG TECH ENGINEERIN (CN) 1998-10-28 CN claimed
US-5654281-A Inhibiting the development of tolerance to and/or dependence on an addictive substance VIRGINIA COMMONWEALTH UNIVERSITY (US) 1997-08-05 US claimed
EP-0608893-A1 Inhibiting the development of tolerance to and/or dependence on an additive substance VIRGINIA COMMONWEALTH UNIVERSITY (US) 1994-08-03 EP claimed
US-4126684-A 4-AMINO-3-P-HALOPHENYLBUTYRIC ACIDS AND THEIR DERIVATIVES USED IN THE CONTROL OF NARCOTIC ABUSE CIBA-GEIGY CORPORATION (US) 1978-11-21 US claimed