Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 1/20 | 0.50 |
| ▸ | SKP1 | P63208 | 1/20 | 0.50 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.45 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.45 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 5/20 | 0.43 |
| ▸ | ACACA | Q13085 | 5/20 | 0.43 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16449186 | 0.87 | CKS1B (0.52) | CKS1BSKP1SKP2OPRK1SIRT2 | |
| SCHEMBL12516424 | 0.85 | CKS1B (0.51) | CKS1BSKP1SKP2OPRK1SIRT2 | |
| SCHEMBL14659830 | 0.83 | CKS1B (0.49) | CKS1BSKP1SKP2OPRK1SIRT2 | |
| SCHEMBL25768619 | 0.81 | CKS1B (0.52) | CKS1BSKP1SKP2ACACBACACA | |
| SCHEMBL2416854 | 0.77 | MEN1 (0.46) | CKS1BSKP1SKP2 | |
| SCHEMBL30394316 | 0.77 | MEN1 (0.46) | CKS1BSKP1SKP2 | |
| SCHEMBL12082925 | 0.76 | CKS1B (0.54) | CKS1BSKP1SKP2SIRT2SIRT1 | |
| SCHEMBL30376168 | 0.76 | CKS1B (0.52) | CKS1BSKP1SKP2SIRT2SIRT1 | |
| SCHEMBL21533025 | 0.75 | CKS1B (0.48) | CKS1BSKP1SKP2SIRT2SIRT1 | |
| SCHEMBL16449187 | 0.74 | CKS1B (0.50) | CKS1BSKP1SKP2SIRT2SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116835-A1 | MULTI-PROTEIN DEGRADATION AGENT HAVING IMIDE SKELETON | 苏州开拓药业股份有限公司 | 2023-06-29 | — | — | WO | disclosed |