Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 2/20 | 0.52 |
| ▸ | SKP1 | P63208 | 2/20 | 0.52 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.52 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 7/20 | 0.43 |
| ▸ | ACACA | Q13085 | 6/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | RBP4 | P02753 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25768617 | 0.81 | CKS1B (0.50) | CKS1BSKP1SKP2FGFR3KDR | |
| SCHEMBL25768937 | 0.81 | CNR2 (0.42) | CHRM4F10RBP4CNR2 | |
| SCHEMBL25769166 | 0.81 | TRPA1 (0.54) | CKS1BSKP1SKP2RBP4CNR2 | |
| SCHEMBL25768620 | 0.79 | PTPN11 (0.48) | KDRRBP4CNR2 | |
| SCHEMBL25768737 | 0.78 | HSD11B1 (0.43) | DRD2RBP4CNR2 | |
| SCHEMBL25767971 | 0.76 | CXCR4 (0.41) | CHRM4RBP4CNR2 | |
| SCHEMBL25765960 | 0.76 | F10 (0.42) | CKS1BSKP1SKP2CHRM4F10 | |
| SCHEMBL25767250 | 0.73 | CNR2 (0.48) | RBP4CNR2 | |
| SCHEMBL2274801 | 0.73 | CXCR3 (0.51) | CKS1BSKP1SKP2DRD2ACACB | |
| SCHEMBL12082500 | 0.72 | CKS1B (0.54) | CKS1BSKP1SKP2DRD2ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116835-A1 | MULTI-PROTEIN DEGRADATION AGENT HAVING IMIDE SKELETON | 苏州开拓药业股份有限公司 | 2023-06-29 | — | — | WO | disclosed |