Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NMT1 | P30419 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24158449 | 0.86 | TGM2 (0.43) | TGM2MAPTALDH1A1 | |
| SCHEMBL26433462 | 0.77 | TGM2 (0.53) | TGM2POLBTDP1MAPTNPC1 | |
| SCHEMBL19383721 | 0.70 | TRPA1 (0.32) | — | |
| SCHEMBL26080318 | 0.68 | TGM2 (0.35) | TGM2 | |
| SCHEMBL15292671 | 0.67 | TGM2 (0.47) | TGM2POLBMAPTALDH1A1NPC1 | |
| SCHEMBL20008068 | 0.67 | TGM2 (0.47) | TGM2POLBMAPTALDH1A1NPC1 | |
| SCHEMBL20912080 | 0.66 | TGM2 (0.47) | TGM2POLBTDP1MAPTALDH1A1 | |
| SCHEMBL13626039 | 0.66 | MAPT (0.45) | TGM2POLBTDP1MAPTALDH1A1 | |
| SCHEMBL648950 | 0.65 | TGM2 (1.00) | TGM2POLBTDP1ALDH1A1NPC1 | |
| SCHEMBL22959433 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4206184-A1 | PHENOL DERIVATIVE | Sumitomo Pharma Co., Ltd. (JP) | 2023-07-05 | — | — | EP | disclosed |