Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 7/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.39 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 4/20 | 0.33 |
| ▸ | CES1 | P23141 | 4/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11766669 | 0.91 | DNM1 (0.46) | EPHX2DNM1KDM5AKDM4CPHF8 | |
| SCHEMBL15997772 | 0.89 | DNM1 (0.42) | EPHX2DNM1KDM5AKDM4CPHF8 | |
| SCHEMBL21880763 | 0.87 | DNM1 (0.46) | EPHX2DNM1S1PR2S1PR1S1PR3 | |
| SCHEMBL18596717 | 0.87 | DNM1 (0.46) | EPHX2DNM1S1PR2S1PR1S1PR3 | |
| SCHEMBL17936461 | 0.85 | DNM1 (0.42) | EPHX2DNM1KDM5AKDM4CPHF8 | |
| SCHEMBL25093997 | 0.84 | EPHX2 (0.41) | EPHX2DNM1KDM5AKDM4CPHF8 | |
| SCHEMBL22304537 | 0.83 | DNM1 (0.41) | DNM1CES2CES1 | |
| SCHEMBL18458859 | 0.83 | DNM1 (0.46) | EPHX2DNM1S1PR2S1PR1S1PR3 | |
| SCHEMBL26075078 | 0.80 | EPHX2 (0.37) | EPHX2DNM1KDM5AKDM4CPHF8 | |
| SCHEMBL22986133 | 0.78 | DNM1 (0.41) | EPHX2DNM1KDM5AKDM4CPHF8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4206325-A1 | NOVEL NUCLEIC ACID MOLECULE INHIBITING EXPRESSION OF TARGET GENE | BONAC CORPORATION (JP) | 2023-07-05 | — | — | EP | disclosed |